INTRODUCTION
The Pharma Industry is an essential component of the healthcare system throughout the world. It is mainly based upon scientific research and the development of injectables that prevent and treat various diseases and disorders. From discovering the active ingredient to manufacturing the finished product, the production of a drug is time-consuming, complex, and expensive.
However, the administration of drugs through injection to a human body was recorded first in the mid-1800s. Later in the 1900s, it became a viable process when the knowledge of microorganisms and sterilization techniques became more common. Nonetheless, sterilization techniques were extremely damaging to drug products till the time HEPA filters, sterilizing filters, and clean rooms became more common.
Injectable drug products can be made into several different types depending on the characteristic of the drug, desired onset action of the drug, and the required root of administration. They are mainly divided into three categories:
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- Injectable solution: This drug is dissolved in water or additives, known as excipients, to help stabilize it.
- Injectable suspension: These drug crystals are not soluble in water, so the surface of the crystals is wetted to prevent them from floating on the solution surface; this is accomplished with a surfactant. This agent protects the crystals to settle at the button in the form of a solid.
- Injectable emulsion: This drug is not soluble in water; therefore, it is dissolved in the oil; which is further added to water with an emulsifying agent. Then it is mixed with a high-shear mixture to reduce the oil droplets to micron-sized drops. Thus, forever remaining as drops due to the emulsifying agent (surfactant).
- Injectable solution: This drug is dissolved in water or additives, known as excipients, to help stabilize it.
After the formulation and pre-formulation steps are conducted on the drug, it is filtered, filled, stoppered, capped, lyophilized, inspected, labeled, and packed. However, to make your injectable manufacturing process polished and untroubled Wahal Engineers introduce a wide range of machines such as:
- Planetary Mixer/Double Planetary Mixers: Wahal Engineers developed and extended the horizon of Planetary Mixer by incorporating High Viscosity Blades in design, raising the maximum viscosity range to around 6 million cP. Thus, offering better cleanability, a smaller footprint, and lower capital cost. Wahals’ PowerMix Planetary Disperser (PDM) reaches high enough viscosities where kneading can be effective and are designed for high shear intensity and faster solids dispersion. This being our latest addition to the planetary mixing line of industrial mixers known as the Planetary Dual Disperser (PDDM). PDDM delivers uninterrupted processing power for advanced batteries, adhesives, composites, pharmaceuticals, coatings, and chemicals.
Planetary Disperser (PDM)
Sigma Mixers (Z arm Mixers): Sigma/ Z Blade Mixer is used for uniform mixing of semi-solid materials. It consists of a U trough with two ‘Z’ shape blades, each rotating in opposite directions for proper mixing of material. It is equipped with a suitable capacity motor & gearbox and is most suitable for uniformly mixing pasty and thick materials.
Sigma Mixer (Z arm Mixer – Blade Mixer)
Intermediate Bulk Containers (IBC) Tank Mixers: Wahal Engineers’ unique new range of Industrial Homogenizers are designed for use with plastic transportable Intermediate Bulk Containers (IBC). We supply a range of models suitable for a variety of applications, including – Mixing, blending, and homogenization of light viscous liquid as well as for re-suspension of settled solids and dissolution of powders.
IBC Tank (Intermediate Bulk Containers)
Ribbon Blenders Mixers: It is a basic industrial mixing machine that consists of a trough-shaped shell with a semicircular bottom fitted within a horizontal longitudinal shaft. It is mounted with arms that support a combination of ribbon blades, paddles, or helical screws set at a close clearance to the semicircular mixer body, thus ensuring no layer of material remains on the bottom of the ribbon mixer. Wahal Engineer provides an efficient design of ribbon layout double spiral in which the outer ribbon moves the product in one direction, and the inner ribbon moves it in the opposite direction.
Each of our products thrives for providing a better solution, meeting new technology, and providing higher efficiency. Our solutions are the best in the industry, and our goal is to ensure customer satisfaction. So take advantage of them right away!